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Article

Multifactor-dimensionality reduction versus family-based association tests in detecting susceptibility loci in discordant sib-pair studies.

BMC genetics - 30 Dec 2005

Meng Yan, Ma Qianli, Yu Yi, Farrell John, Farrer Lindsay A, Wilcox Marsha A

Abstract excerpt

Complex diseases are generally thought to be under the influence of multiple, and possibly interacting, genes. Many association methods have been developed to identify susceptibility genes assuming a single-gene disease model, referred to as single-locus methods. Multilocus methods consider joint effects of multiple genes and environmental factors. One commonly used method for family-based association analysis is...

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Identifiers

PMID: 16451606
DOI: 10.1186/1471-2156-6-S1-S146
PMCID: PMC1866789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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