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Article

Variation of the mexT gene, a regulator of the MexEF-oprN efflux pump expression in wild-type strains of Pseudomonas aeruginosa.

FEMS microbiology letters - 1 Nov 2000

Maseda H, Saito K, Nakajima A, Nakae T

Abstract excerpt

We found three variations of wild-type strains in terms of mexT-mediated regulation of the MexEF-OprN efflux pump, in which overexpression of the pump results in nfxC-type antibiotic resistance in Pseudomonas aeruginosa. Type-I: the mexT gene of the wild-type strain encoded inactive MexT and the nfxC-type mutants derived from this parent had an additional mutation in mexT converting MexT from the inactive to the...

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PMID: 11040437
DOI: 10.1111/j.1574-6968.2000.tb09367.x

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