Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery

30 Jan 2006

Abstract excerpt

In order to assess a new strategy of DNA vaccine for a more complete understanding of its action in immune response, it is important to determine the in vivo biodistribution fate and antigen expression. In previous studies, our group focused on the prophylactic and therapeutic use of a plasmid DNA encoding the Mycobacterium leprae 65-kDa heat shock protein (Hsp65) and achieved an efficient immune response...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Escherichia coli research studies
Share to Hepatitis B Virus Studies
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16445866
DOI: 10.1186/1479-0556-4-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular deliveryPMID 16445866Read ↗

Plasmid DNA vaccines: assay for integration into host genomic DNA.Semantic proximity Read ↗

Improvement of DNA vaccination by adjuvants and sophisticated delivery devices: vaccine-platforms for the battle against infectious diseasesSemantic proximity Read ↗

DNA vaccinesSemantic proximity Read ↗

Plasmid DNA Malaria Vaccine: The Potential for Genomic Integration after Intramuscular InjectionSemantic proximity Read ↗

Vaccination with Plasmid DNA Encoding Mycobacterial Antigen 85A Stimulates a CD4<sup>+</sup>and CD8<sup>+</sup>T-Cell Epitopic Repertoire Broader than That Stimulated by<i>Mycobacterium tuberculosis</i>H37Rv InfectionSemantic proximity Read ↗

Recent Developments in Preclinical DNA VaccinationSemantic proximity Read ↗

Plasmid DNA Vaccines: Investigation of Integration into Host Cellular DNA following Intramuscular Injection in MiceSemantic proximity Read ↗

Transcriptional dysregulation of inflammatory/immune pathways after active vaccination against Huntington′s diseaseSemantic proximity Read ↗

CpG Methylation of a Plasmid Vector Results in Extended Transgene Product Expression by Circumventing Induction of Immune ResponsesSemantic proximity Read ↗

Inhibition of adjuvant‐induced arthritis by DNA vaccination with the 70‐kd or the 90‐kd human heat‐shock protein: Immune cross‐regulation with the 60‐kd heat‐shock proteinSemantic proximity Read ↗

Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A*0201-restricted T-cell epitopes of Mycobacterium tuberculosisSemantic proximity Read ↗

Bacteria-mediated DNA transfer in gene therapy and vaccinationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.