Article
Effect of various genetic polymorphisms on the incidence and outcome of severe sepsis.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jan 2006
Sipahi Tansu, Pocan Hatice, Akar Nejat
Abstract excerpt
Several genetic polymorphisms have been identified in patients with sepsis and severe sepsis, such as the tumor necrosis factor-alpha (TNF-alpha) and TNF-beta genes, the interleukin-1 (IL-1) family, the IL-6, the IL-10, the CD-14, the Toll-like receptors, plasminogen activator inhibitor type 1, and the factor V 1691G-A mutations. In this study, the relationship between the TNF-alpha 308G/A, the IL-6-174 G/C, the...
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