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Article

Functional analysis of hepatitis C virus envelope proteins, using a cell-cell fusion assay.

Journal of virology - 1 Feb 2006

Kobayashi Mariko, Bennett Michael C, Bercot Theodore, Singh Ila R

Abstract excerpt

Hepatitis C virus (HCV) envelope proteins mediate the entry of virus into cells by binding to cellular receptors, resulting in fusion of the viral membrane with the host cell membrane and permitting the viral genome to enter the cytoplasm. We report the development of a robust and reproducible cell-cell fusion assay using envelope proteins from commonly occurring genotypes of HCV. The assay scored HCV envelope...

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Identifiers

PMID: 16439538
DOI: 10.1128/JVI.80.4.1817-1825.2006
PMCID: PMC1367170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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