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Article

Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation.

The Journal of biological chemistry - 24 Mar 2006

Lee Yoon-Kwang, Choi Yun-Hee, Chua Steven, Park Young Joo, Moore David D

Abstract excerpt

The nuclear receptor LRH-1 (NR5A2) functions to regulate expression of a number of genes associated with bile acid homeostasis and other liver functions, but mechanisms that modulate its activity remain unclear. We have found that mitogenic stimuli, including treatment with phorbol myristate (PMA...

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Identifiers

PMID: 16439367
DOI: 10.1074/jbc.M509115200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16439367-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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