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Article

Glucuronidation and susceptibility to chemical carcinogenesis.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Mar 2004

Wallig Matthew A

Abstract excerpt

The highlighted article in this issue of Toxicological Sciences, written by Zhuohan Hu and Peter Wells, addresses a subject that has received increasing scrutiny the past decade and a half--interindividual variation in detoxification enzyme activity as it relates to toxicity and cancer. Hu and Wells in their simple yet elegant study report variations in glucuronidation among normal individuals and provide data...

Topics

Biotransformation
Carcinogens
Genotype
Glucuronides
Glucuronosyltransferase
Neoplasms
Polymorphism, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15025107
DOI: 10.1093/toxsci/kfh068

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