Article
Polymorphism of drug-metabolizing enzymes in relation to individual susceptibility to industrial chemicals.
Industrial health - 1 Apr 2000
Nakajima T, Aoyama T
Abstract excerpt
Polymorphism and the induction/inhibition of drug-metabolizing enzymes, such as cytochrome P450, aldehyde dehydrogenase (ALDH), glutathione S-transferase (GST), N-acetyltransferase (NAT), and NAD(P)H-quinone oxidoreductase (NQO1), were reviewed in relation to susceptibility to disease and to inter-individual difference in biological monitorings. A number of genetic and acquired factors can influence the...
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