Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival.

Journal of the American Society of Nephrology : JASN - 1 Mar 2006

Eremina Vera, Cui Shiying, Gerber Hanspeter, Ferrara Napoleone, Haigh Jody, Nagy Andras, Ema Masatsugu, Rossant Janet, Jothy Serge, Miner Jeffrey H, Quaggin Susan E

Abstract excerpt

The glomerular filtration barrier separates the blood from the urinary space and consists of two major cell types: podocytes and fenestrated endothelial cells. Mesangial cells sit between the capillary loops and provide structural support. Proliferation and loss of mesangial cells both are central findings in a number of renal diseases, including diabetic nephropathy and mesangiolysis, respectively. Using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Death
Share to Cell Movement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Glomerular Mesangium

Share to In Situ Hybridization

Share to Podocytes

Share to Probability

Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 16436493
DOI: 10.1681/ASN.2005080810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival.PMID 16436493Read ↗

The role of VEGF-A in glomerular development and functionSemantic proximity Read ↗

Forced expression of vascular endothelial growth factor-A in podocytes decreases mesangial cell numbers and attenuates endothelial cell differentiation in the mouse glomerulus.Semantic proximity Read ↗

Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus.Semantic proximity Read ↗

Gene expression programs of mouse endothelial cells in kidney development and disease.Semantic proximity Read ↗

Hypoxia and podocyte-specificVhlhdeletion confer risk of glomerular diseaseSemantic proximity Read ↗

Glomerular-Specific Gene Excision In VivoSemantic proximity Read ↗

Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling.Semantic proximity Read ↗

Mesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1.Semantic proximity Read ↗

Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney developmentSemantic proximity Read ↗

One hundred ways to kill a podocyte: FIGURE 1:Semantic proximity Read ↗

Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D.Semantic proximity Read ↗

VEGF-A loss in the haematopoietic and endothelial lineages exacerbates age-induced renal changes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.