Article
Extended tracts of homozygosity in outbred human populations.
Human molecular genetics - 1 Mar 2006
Gibson Jane, Morton Newton E, Collins Andrew
Abstract excerpt
Long tracts of consecutive homozygous single nucleotide polymorphisms (SNPs) can arise in the genome through a number of mechanisms. These include inbreeding in which an individual inherits chromosomal segments that are identical by descent from each parent. However, recombination and other processes break up chromosomal segments over generations. The longest tracts are therefore to be expected in populations...
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