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Article

The architecture of long-range haplotypes shared within and across populations.

Molecular biology and evolution - 1 Feb 2012

Gusev Alexander, Palamara Pier Francesco, Aponte Gregory, Zhuang Zhong, Darvasi Ariel, Gregersen Peter, Pe'er Itsik

Abstract excerpt

Homologous long segments along the genomes of close or remote relatives that are identical by descent (IBD) from a common ancestor provide clues for recent events in human genetics. We set out to extensively map such IBD segments in large cohorts and investigate their distribution within and across different populations. We report analysis of several data sets, demonstrating that IBD is more common than expected...

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Identifiers

PMID: 21984068
DOI: 10.1093/molbev/msr133
PMCID: PMC3350316

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