Article
A (G->C) transversion in the 3' UTR of the human ECP (eosinophil cationic protein) gene correlates to the cellular content of ECP.
Journal of leukocyte biology - 1 Apr 2006
Jönsson Ulla-Britt, Byström Jonas, Stålenheim Gunnemar, Venge Per
Abstract excerpt
Eosinophil cationic protein (ECP) is a cytotoxic protein produced by and secreted from human eosinophil granulocytes. ECP may be involved in the injury of epithelial cells in allergic diseases such as asthma. The objectives were to determine the prevalence of the ECP gene polymorphism 562(G > C) in apparently healthy subjects and subjects with allergy and relate the prevalence to clinical disease and to serum and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
