Article
Eosinophil cationic protein--current concepts and controversies.
Biochemia medica - 1 Jan 2011
Topic Renata Zrinski, Dodig Slavica
Abstract excerpt
Eosinophil cationic protein (ECP) is a heterogeneous molecule originating from activated eosinophil granulocytes. Biological activity and the cellular content of ECP are determined by genetic and posttranslational factors. Several single nucleotide polymorphisms (SNPs) in human ECP gene (RNASE3) have been described so far. ECP is a mediator in host immune response to parasites, bacteria and viruses. By its...
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