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Article

Asparagine-linked glycans determine the cytotoxic capacity of eosinophil cationic protein (ECP).

Molecular immunology - 1 Oct 2013

Rubin Jenny, Venge Per

Abstract excerpt

Eosinophil cationic protein (ECP) is a toxic, granule-stored protein of the eosinophil granulocyte. It is a heterogeneous protein; molecular weights can differ from 15 to 22 kDa, due to glycosylations. We purified high molecular weight ECP from blood donors with the ECP434GG (rs2073342) genotype, with the aim of examining whether removal of carbohydrates could enhance the cytotoxic capacity. The cytotoxic...

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Source

Identifiers

PMID: 23597768
DOI: 10.1016/j.molimm.2013.03.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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