Article
The promoter polymorphism in the eosinophil cationic protein gene and its influence on the serum eosinophil cationic protein level.
American journal of respiratory and critical care medicine - 15 Jan 2003
Noguchi Emiko, Iwama Asushi, Takeda Kazunori, Takeda Tetsuya, Kamioka Masashi, Ichikawa Kunio, Akiba Toshiko, Arinami Tadao, Shibasaki Masanao
Abstract excerpt
Asthma is characterized by reversible airway obstruction and airway inflammation. Serum levels of eosinophil cationic protein (ECP) might reflect eosinophilic airway inflammation and asthma activity. However, serum ECP levels are not elevated in some patients with asthma, even when they are symptomatic. In this study, we screened for polymorphisms in the ECP gene and analyzed association between these...
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