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Article

Identification of polymorphisms in the RNase3 gene and the association with allergic rhinitis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Mar 2010

Kang Inhong, An Xue-hua, Oh Yeon-Kyun, Lee Sang Heon, Jung Ha Min, Chae Soo-Cheon, Lee Jae Hoon

Abstract excerpt

Eosinophil cationic protein (ECP), a potent cytotoxic molecule, is released by activated eosinophils. ECP has been suggested to be involved in tissue remodeling of allergic diseases. The ECP (RNase3) gene is a candidate gene in atopic diseases. RNase3 polymorphisms have been reported to have an association with atopy. We determined whether polymorphisms in the RNase3 gene are associated with allergic rhinitis in...

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PMID: 19760211
DOI: 10.1007/s00405-009-1103-8

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Source receipt: pubmed, retrieved 7 Sept 2026.

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