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Article

The effect of phenotype on mechanical stretch-induced vascular smooth muscle cell apoptosis.

Journal of vascular research - 1 Jan 2006

Su Baogen Y, Shontz Kimberly M, Flavahan Nicholas A, Nowicki Philip T

Abstract excerpt

The present study evaluated mechanical stretch-induced apoptosis in swine vascular smooth muscle cells (VSMC) of different phenotypes. We demonstrated that differentiated VSMC express a greater level of Bcl-2-associated death factor (BAD) and have a significant cell loss when exposed to mechanical stretch (10% elongation, 1 Hz) for 24 h. We further demonstrated that apoptosis was significantly increased only in...

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Share to bcl-Associated Death Protein
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Share to Muscle, Smooth, Vascular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myocytes, Smooth Muscle

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Share to Proto-Oncogene Proteins c-bcl-2

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Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 16432304
DOI: 10.1159/000091102

Genes

BAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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