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Article

Up-regulation of NFkappaB-responsive gene expression by DeltaNp73alpha in p53 null cells.

Experimental cell research - 1 May 2006

Tanaka Yasuharu, Ota Katsuya, Kameoka Masanori, Itaya Asako, Yoshihara Koichiro

Abstract excerpt

Transactivation domain (TAD)-truncated p73, DeltaNp73, associates with p53, resulting in suppression of p53's functions. Using p53 null cell lines, we examined whether or not DeltaNp73 can regulate gene expression in a p53-independent manner. When DeltaNp73alpha was co-transfected with a luciferase reporter plasmid with various enhancer elements, NFkappaB-responsive luciferase gene expression was selectively...

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Identifiers

PMID: 16430884
DOI: 10.1016/j.yexcr.2005.12.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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