Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of gluconeogenesis and the tricarboxylic acid cycle in the virulence of Salmonella enterica serovar Typhimurium in BALB/c mice.

Infection and immunity - 1 Feb 2006

Tchawa Yimga Merlin, Leatham Mary P, Allen James H, Laux David C, Conway Tyrrell, Cohen Paul S

Abstract excerpt

In Salmonella enterica serovar Typhimurium, the Cra protein (catabolite repressor/activator) regulates utilization of gluconeogenic carbon sources by activating transcription of genes in the gluconeogenic pathway, the glyoxylate bypass, the tricarboxylic acid (TCA) cycle, and electron transport and repressing genes encoding glycolytic enzymes. A serovar Typhimurium SR-11 Deltacra mutant was recently reported to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Citric Acid Cycle
Share to Colony Count, Microbial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Media

Share to Gluconeogenesis

Share to Glucose

Share to Mice, Inbred BALB C

Share to Salmonella Infections, Animal

Share to Salmonella typhimurium

Source

Open in PubMed Open full text

Identifiers

PMID: 16428761
DOI: 10.1128/IAI.74.2.1130-1140.2006
PMCID: PMC1360343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Role of gluconeogenesis and the tricarboxylic acid cycle in the virulence of Salmonella enterica serovar Typhimurium in BALB/c mice.PMID 16428761Read ↗

Salmonella enterica serovar Typhimurium mutants unable to convert malate to pyruvate and oxaloacetate are avirulent and immunogenic in BALB/c mice.Semantic proximity Read ↗

Diarrhea and colitis in mice require the Salmonella pathogenicity island 2-encoded secretion function but not SifA or Spv effectors.Semantic proximity Read ↗

An incomplete TCA cycle increases survival of Salmonella Typhimurium during infection of resting and activated murine macrophages.Semantic proximity Read ↗

Glucose and Glycolysis Are Required for the Successful Infection of Macrophages and Mice by Salmonella enterica Serovar TyphimuriumSemantic proximity Read ↗

Mutation of phosphotransacetylase but not isocitrate lyase reduces the virulence of Salmonella enterica serovar Typhimurium in mice.Semantic proximity Read ↗

The In Vitro Redundant Enzymes PurN and PurT Are Both Essential for Systemic Infection of Mice in Salmonella enterica Serovar Typhimurium.Semantic proximity Read ↗

Cra-mediated regulation of Escherichia coli adenylate cyclase.Semantic proximity Read ↗

FNR is a global regulator of virulence and anaerobic metabolism in Salmonella enterica serovar Typhimurium (ATCC 14028s).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.