Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cra-mediated regulation of Escherichia coli adenylate cyclase.

Microbiology (Reading, England) - 1 Mar 1997

Crasnier-Mednansky Martine, Park Maxwell C, Studley William K, Saier Milton H

Abstract excerpt

In Escherichia coli, expression of certain genes and operons, including the fructose operon, is controlled by Cra, the pleiotropic catabolite repressor/activator protein formerly known as FruR. In this study we have demonstrated that cra mutant strains synthesize 10-fold less cAMP than isogenic wild-type strains, specifically when grown in fructose-containing minimal media. The glucose-specific IIA protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Bacterial Proteins
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli Proteins

Share to Gene Expression Regulation, Bacterial

Share to Gene Expression Regulation, Enzymologic

Share to Mutation

Share to Repressor Proteins

Source

Identifiers

PMID: 9084162
DOI: 10.1099/00221287-143-3-785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cra-mediated regulation of Escherichia coli adenylate cyclase.PMID 9084162Read ↗

CRP down-regulates adenylate cyclase activity by reducing the level of phosphorylated IIA(Glc), the glucose-specific phosphotransferase protein, in Escherichia coli.Semantic proximity Read ↗

Effect of replacing the general energy-coupling proteins of the PEP:sugar phosphotransferase system of Salmonella typhimurium with their fructose-inducible counterparts on utilization of the PTS sugar glucitol.Semantic proximity Read ↗

A global regulatory role of gluconeogenic genes in Escherichia coli revealed by transcriptome network analysis.Semantic proximity Read ↗

Biofilm formation in Escherichia coli cra mutants is impaired due to down-regulation of curli biosynthesis.Semantic proximity Read ↗

Phosphotransferase system sugars immediately induce mutations of Cra in an Escherichia coli ptsH mutant.Semantic proximity Read ↗

Cyclic AMP-dependent catabolite repression is the dominant control mechanism of metabolic fluxes under glucose limitation in Escherichia coli.Semantic proximity Read ↗

Physiological consequences of the complete loss of phosphoryl-transfer proteins HPr and FPr of the phosphoenolpyruvate:sugar phosphotransferase system and analysis of fructose (fru) operon expression in Salmonella typhimurium.Semantic proximity Read ↗

Expression of ptsG encoding the major glucose transporter is regulated by ArcA in Escherichia coli.Semantic proximity Read ↗

Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway.Semantic proximity Read ↗

Genetic and biochemical analysis of the adenylyl cyclase of Schizosaccharomyces pombe.Semantic proximity Read ↗

Transcriptional regulators of the Schizosaccharomyces pombe fbp1 gene include two redundant Tup1p-like corepressors and the CCAAT binding factor activation complex.Semantic proximity Read ↗

A cyclic AMP receptor protein mutant that constitutively activates an Escherichia coli promoter disrupted by an IS5 insertion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.