Article
FNR is a global regulator of virulence and anaerobic metabolism in Salmonella enterica serovar Typhimurium (ATCC 14028s).
Journal of bacteriology - 1 Mar 2007
Fink Ryan C, Evans Matthew R, Porwollik Steffen, Vazquez-Torres Andres, Jones-Carson Jessica, Troxell Bryan, Libby Stephen J, McClelland Michael, Hassan Hosni M
Abstract excerpt
Salmonella enterica serovar Typhimurium must successfully transition the broad fluctuations in oxygen concentrations encountered in the host. In Escherichia coli, FNR is one of the main regulatory proteins involved in O2 sensing. To assess the role of FNR in serovar Typhimurium, we constructed an isogenic fnr mutant in the virulent wild-type strain (ATCC 14028s) and compared their transcriptional profiles and...
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