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Article

Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p.

RNA (New York, N.Y.) - 1 Feb 2006

Bellare Priya, Kutach Alan K, Rines Amy K, Guthrie Christine, Sontheimer Erik J

Abstract excerpt

The U1, U2, U4/U6, and U5 small nuclear ribonucleoproteins (snRNPs) are components of the spliceosome, which catalyzes pre-mRNA splicing. One of the largest and the most highly conserved proteins in the spliceosome is Prp8p, a component of the U5 snRNP. Despite its size and conservation, very few motifs have been identified that suggest specific biochemical functions. A variant of the Jab1/MPN domain found in a...

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Identifiers

PMID: 16428608
DOI: 10.1261/rna.2152306
PMCID: PMC1370909

Genes

UBD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p.PMID 16428608Read ↗

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