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Article

Functional analysis of biologically distinct genetic variants of simian immunodeficiency virus isolated from a mandrill.

Virology - 1 Jul 1992

Sakai H, Sakuragi J, Sakuragi S, Shibata R, Adachi A

Abstract excerpt

We examined the biological properties of two infectious clones of a simian immunodeficiency virus, SIVMND, which were designated as pMD121 and pMD122. Upon transfection into CD4-negative cells, pMD122 generated virions much less efficiently than pMD121. Likewise, the growth kinetics in CD4-positive cells of virus derived from pMD122 were remarkably delayed relative to those of virus from pMD121. The cytocidal...

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PMID: 1604807
DOI: 10.1016/0042-6822(92)90691-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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