Article
Polymorphisms of DNA repair genes XRCC1 and XRCC3, interaction with environmental exposure and risk of chronic gastritis and gastric cancer.
World journal of gastroenterology - 14 Nov 2005
Duarte Márcia Cristina, Colombo Jucimara, Rossit Andrea Regina Baptista, Caetano Alaor, Borim Aldenis Albaneze, Wornrath Durval, Silva Ana Elizabete
Abstract excerpt
AIM: To evaluate the association between polymorphisms XRCC1 Arg194Trp and Arg399Gln and XRCC3 Thr241Met and the risk for chronic gastritis and gastric cancer, in a Southeastern Brazilian population. METHODS: Genotyping by PCR-RFLP was carried out on 202 patients with chronic gastritis (CG) and 160 patients with gastric cancer (GC), matched to 202 (C1) and 150 (C2) controls, respectively. RESULTS: No differences...
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