Article
Genetic polymorphism of XRCC3 codon 241 and Helicobacter pylori infection-related gastric antrum adenocarcinoma in Guangxi Population, China: a hospital-based case-control study.
Cancer epidemiology - 1 Dec 2011
Zhao Lei, Long Xi-Dai, Yao Jin-Guang, Wang Chao, Ma Yun, Huang Yong-Zhi, Li Yun-Qian, Wang Min-Fa, Fu Guo-Hui
Abstract excerpt
BACKGROUND: The relationship between Helicobacter pylori infection and gastric antrum adenocarcinoma (GAA) has previously been demonstrated and supported with strong epidemiological evidence. However, the role of genetic polymorphism of X-ray cross-complementing group 3 (XRCC3) Thr241Met (rs#861539), which may be involved in the repair of DNA double-strand breaks caused by carcinogens such as CagA, a protein...
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