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Article

Polymorphisms of DNA repair and xenobiotic genes predispose to CpG island methylation in non-neoplastic gastric mucosa.

Helicobacter - 1 Apr 2011

Tahara Tomomitsu, Shibata Tomoyuki, Nakamura Masakatsu, Okubo Masaaki, Yamashita Hiromi, Yoshioka Daisuke, Yonemura Joh, Ishizuka Takamitsu, Hirata Ichiro, Arisawa Tomiyasu

Abstract excerpt

BACKGROUND: Genetic factors, related to DNA repair or xenobiotic pathways might confer different degrees of susceptibility to gastric carcinogenesis. CpG island hyper methylation (CIHM) is a major event in gastric carcinogenesis. We evaluated the association between XRCC1, GSTP1, GSTT1 and GSTM1 polymorphisms with CIHM status in non-neoplastic gastric mucosa. METHODS: XRCC1 Arg399Gln, and Arg194Trp, GSTP1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21435086
DOI: 10.1111/j.1523-5378.2011.00821.x

Genes

XRCC1
GSTM1
DAP
GSTP1
GSTT1
CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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