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Article

Methylation of the ASC gene promoter is associated with aggressive prostate cancer

19 Jan 2006

Abstract excerpt

BACKGROUND: The aim of this study was to investigate the methylation status of apoptosis-associated speck-like protein containing a CARD (ASC; TMS1; PYCARD) in prostate cancer cell lines and human tissues and to determine if those findings correlate with the clinicopathological features of prostate cancer. METHODS: Genomic DNA was isolated from prostate cell lines and microdissected tissues, bisulfite converted...

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PMID: 16425203
DOI: 10.1002/pros.20371

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