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Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer

17 Feb 1998

Abstract excerpt

The identification of cell surface antigens is critical to the development of new diagnostic and therapeutic modalities for the management of prostate cancer. Prostate stem cell antigen (PSCA) is a prostate-specific gene with 30% homology to stem cell antigen 2, a member of the Thy-1/Ly-6 family of glycosylphosphatidylinositol (GPI)-anchored cell surface antigens. PSCA encodes a 123-aa protein with an...

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PMID: 9465086
DOI: 10.1073/pnas.95.4.1735

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