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Article

Epigenetic Inactivation of <b> <i>TMS1/ASC</i> </b> in Ovarian Cancer

15 Mar 2004

Abstract excerpt

PURPOSE: The purpose of this work was to explore the role of epigenetic inactivation of apoptotic pathways in ovarian cancer by examining the DNA methylation and expression status of four proapoptotic genes in primary ovarian cancers and cancer cell lines and to correlate those findings with the clinicopathological features of ovarian cancer patients. EXPERIMENTAL DESIGN: Genomic DNA was isolated from 15 ovarian...

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PMID: 15041718
DOI: 10.1158/1078-0432.ccr-0932-03

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