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Article

Examination of actin and microtubule dependent APC localisations in living mammalian cells.

BMC cell biology - 19 Jan 2006

Langford Kelly J, Askham Jon M, Lee Tracy, Adams Matthew, Morrison Ewan E

Abstract excerpt

BACKGROUND: The trafficking of the adenomatous polyposis coli (APC) tumour suppressor protein in mammalian cells is a perennially controversial topic. Immunostaining evidence for an actin-associated APC localisation at intercellular junctions has been previously presented, though live imaging of mammalian junctional APC has not been documented. RESULTS: Using live imaging of transfected COS-7 cells we observed...

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Source

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Identifiers

PMID: 16423286
DOI: 10.1186/1471-2121-7-3
PMCID: PMC1386658

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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