Article
Dihydropyrimidine dehydrogenase deficiency in an Indian population.
Cancer chemotherapy and pharmacology - 1 Sept 2006
Saif Muhammad Wasif, Mattison Lori, Carollo Tom, Ezzeldin Hany, Diasio Robert B
Abstract excerpt
BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) deficiency is prevalent in 3-5% of the Caucasian population; however, the frequency of this pharmacogenetic syndrome in the Indian population and other racial and ethnic groups remains to be elucidated. PATIENTS AND METHODS: We describe an Indian patient who presented to clinic for the treatment of gastric adenocarcinoma with 5-flurouracil (5-FU) therapy who...
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