Article
An electronic sensor array for label-free detection of single-nucleotide polymorphisms.
Biosensors & bioelectronics - 15 May 2013
Shen Wei, Deng Huimin, Ren Yuqian, Gao Zhiqiang
Abstract excerpt
A highly sensitive and selective electronic sensor array for label-free detection of single-nucleotide polymorphisms (SNPs) is described in this work. Its sensing mechanism relies on building target DNA-templated silver nanowires (conductive paths) across a nanogap. Following hybridization with a SNP target, a cocktail of nucleases is applied to the nanogap sensor array. Free capture probes (CPs) and imperfectly...
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