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Article

Advanced aging phenotype is revealed by epigenetic modifications in rat liver after in utero malnutrition.

Aging cell - 1 Oct 2016

Heo Hye J, Tozour Jessica N, Delahaye Fabien, Zhao Yongmei, Cui Lingguang, Barzilai Nir, Einstein Francine Hughes

Abstract excerpt

Adverse environmental exposures of mothers during fetal period predispose offspring to a range of age-related diseases earlier in life. Here, we set to determine whether a deregulated epigenetic pattern is similar in young animals whose mothers' nutrition was modulated during fetal growth to that acquired during normal aging in animals. Using a rodent model of maternal undernutrition (UN) or overnutrition (ON),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27470058
DOI: 10.1111/acel.12505
PMCID: PMC5013021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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