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Prenatal exposure to tobacco smoke sex dependently influences methylation and mRNA levels of the Igf axis in lungs of mouse offspring

27 Jan 2017

Abstract excerpt

Prenatal smoke exposure is a risk factor for abnormal lung development and increased sex-dependent susceptibility for asthma and chronic obstructive pulmonary disease (COPD). Birth cohort studies show genome-wide DNA methylation changes in children from smoking mothers, but evidence for sex-dependent smoke-induced effects is limited. The insulin-like growth factor (IGF) system plays an important role in lung...

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PMID: 28130259
DOI: 10.1152/ajplung.00271.2016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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