Article
Absence of resistance mutations in antiretroviral-naive patients treated with ritonavir-boosted saquinavir.
Antiviral therapy - 1 Jan 2006
Ananworanich Jintanat, Hirschel Bernard, Sirivichayakul Sunee, Ubolyam Sasiwimol, Jupimai Thidarat, Prasithsirikul Wisit, Chetchotisakd Ploenchan, Kiertiburanakul Sasisopin, Munsakul Warangkana, Raksakulkarn Phitsanu, Tansuphasawadikul Somboon, Schutz Malte, Snowden Wendy, Ruxrungtham Kiat
Abstract excerpt
BACKGROUND: There are few data on the selection of resistance by ritonavir-boosted saquinavir (SQV/r), particularly in antiretroviral (ARV)-naive patients. OBJECTIVE: To assess the incidence of virological failure and evolution of resistance in ARV-naive individuals receiving SQV/r in the induction phase of the Staccato trial. METHODS: ARV-naive subjects (n = 272) received SQV/r 1,600/100 mg once daily with two...
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