Article
Efficacy, tolerance, and pharmacokinetics of the combination of stavudine, nevirapine, nelfinavir, and saquinavir as salvage regimen after ritonavir or indinavir failure.
AIDS research and human retroviruses - 20 Jan 2001
Casado J L, Dronda F, Hertogs K, Sabido R, Antela A, Martí-Belda P, Dehertogh P, Moreno S
Abstract excerpt
The high rate of protease inhibitor treatment failure in clinical cohorts makes it necessary to define novel salvage therapies. In a prospective study of 31 HIV-infected patients included in a salvage regimen with stavudine, nevirapine, nelfinavir, and saquinavir, viral load decreased a median of 1.65 log(10) and 1.95 log(10) after 6 and 12 months of treatment, respectively, and 35 and 56% of patients had an HIV...
Topics
- Adult
- Aged
- Anti-HIV Agents
- Drug Combinations
- Drug Resistance, Microbial
- Drug Therapy, Combination
- Female
- HIV
- HIV Infections
- HIV Protease
- HIV Protease Inhibitors
- Humans
- Indinavir