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Article

Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics.

American journal of physiology. Heart and circulatory physiology - 1 Jun 2006

Nahrendorf Matthias, Streif Jörg U, Hiller Karl-Heinz, Hu Kai, Nordbeck Peter, Ritter Oliver, Sosnovik David, Bauer Lisa, Neubauer Stefan, Jakob Peter M, Ertl Georg, Spindler Matthias, Bauer Wolfgang R

Abstract excerpt

A decrease in the supply of ATP from the creatine kinase (CK) system is thought to contribute to the evolution of heart failure. However, previous studies on mice with a combined knockout of the mitochondrial and cytosolic CK (CK(-/-)) have not revealed overt left ventricular dysfunction. The aim of this study was to employ novel MRI techniques to measure maximal myocardial velocity (V(max)) and myocardial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16415075
DOI: 10.1152/ajpheart.01038.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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