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Article

Is there an association between the COMT gene and P300 endophenotypes?

European psychiatry : the journal of the Association of European Psychiatrists - 1 Jan 2006

Bramon E, Dempster E, Frangou S, McDonald C, Schoenberg P, MacCabe J H, Walshe M, Sham P, Collier D, Murray R M

Abstract excerpt

P300 wave anomalies correlate with genetic risk for schizophrenia and constitute a plausible endophenotype for the disease. The COMT gene is thought to influence cognitive performance and to be a susceptibility gene for schizophrenia. Unlike two previous studies, we found no significant influence of the COMT gene on P300 amplitude or latency in 189 individuals examined. The well-supported role of the COMT gene...

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Share to Catechol O-Methyltransferase
Share to Event-Related Potentials, P300

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 16414251
DOI: 10.1016/j.eurpsy.2005.11.001

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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