Article
The hedgehog-related gene wrt-5 is essential for hypodermal development in Caenorhabditis elegans.
Developmental biology - 15 Feb 2006
Hao Limin, Aspöck Gudrun, Bürglin Thomas R
Abstract excerpt
The Caenorhabditis elegans genome encodes a series of hedgehog-related genes, which are thought to have evolved and diverged from an ancestral Hh gene. They are classified into several families based on their N-terminal domains. Here, we analyze the expression and function of a member of the warthog gene family, wrt-5, that lacks the Hint/Hog domain. wrt-5 is expressed in seam cells, the pharynx,...
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