Article
Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly.
Cell - 13 Jan 2006
Foo Shane S, Turner Christopher J, Adams Susanne, Compagni Amelia, Aubyn Deborah, Kogata Naoko, Lindblom Per, Shani Moshe, Zicha Daniel, Adams Ralf H
Abstract excerpt
New blood vessels are initially formed through the assembly or sprouting of endothelial cells, but the recruitment of supporting pericytes and vascular smooth muscle cells (mural cells) ensures the formation of a mature and stable vascular network. Defective mural-cell coverage is associated with the poorly organized and leaky vasculature seen in tumors or other human diseases. Here we report that mural cells...
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