Article
Polymorphisms in inflammation-related genes and risk of gastric cancer (Finland).
Cancer causes & control : CCC - 1 Feb 2006
Kamangar Farin, Abnet Christian C, Hutchinson Amy A, Newschaffer Craig J, Helzlsouer Kathy, Shugart Yin Yao, Pietinen Pirjo, Dawsey Sanford M, Albanes Demetrius, Virtamo Jarmo, Taylor Philip R
Abstract excerpt
Helicobacter pylori infection is an important risk factor for gastric cancer, but <3% of carriers of this organism will ever develop gastric cancer. Since inflammation plays a significant role in gastric carcinogenesis, it has been suggested that polymorphisms in genes involved in inflammatory response may partly explain why only a subgroup of patients infected with H. pylori develop gastric cancer. We compared...
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