Article
Factor VII Deficiency.
Seminars in thrombosis and hemostasis - 1 Jun 2009
Mariani Guglielmo, Bernardi Francesco
Abstract excerpt
The complex formed between the procoagulant serine protease activated factor VII (FVII) and the membrane protein tissue factor, exposed on the vascular lumen upon injury, triggers the initiation of blood clotting. This review describes the clinical picture of FVII deficiency and provides information on diagnosis and management of the disease. FVII deficiency, the most common among the rare congenital coagulation...
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