Article
Implantation of a new porous gelatin-siloxane hybrid into a brain lesion as a potential scaffold for tissue regeneration.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Oct 2006
Deguchi Kentaro, Tsuru Kanji, Hayashi Takeshi, Takaishi Mikiro, Nagahara Mitsuyuki, Nagotani Shoko, Sehara Yoshihide, Jin Guang, Zhang HanZhe, Hayakawa Satoshi, Shoji Mikio, Miyazaki Masahiro, Osaka Akiyoshi, Huh Nam-Ho, Abe Koji
Abstract excerpt
For brain tissue regeneration, any scaffold for migrated or transplanted stem cells with supportive angiogenesis is important once necrotic brain tissue has formed a cavity after injury such as cerebral ischemia. In this study, a new porous gelatin-siloxane hybrid derived from the integration of gelatin and 3-(glycidoxypropyl) trimethoxysilane was implanted as a three-dimensional scaffold into a defect of the...
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