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Biomineralized tetramethylpyrazine-loaded PCL/Gelatin nanofibrous membrane promotes vascularization and bone regeneration of rat cranium defects

2023-08-31

Abstract excerpt

Conventional electrospinning produces nanofibers with smooth surfaces that limit biomineralization ability. To overcome this disadvantage, we fabricated a tetramethylpyrazine (TMP)-loaded matrix-mimicking biomineralization in PCL/Gelatin composite electrospun membranes with bubble-shaped nanofibrous structures. PCL/Gelatin membranes (PG), PCL/Gelatin membranes containing biomineralized hydroxyapatite (HA) (PGH), a...

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Literature Corpus work
a069777b-d83c-5143-a5cb-402738b1a9b0
DOI
10.21203/rs.3.rs-3294726/v1
Open publication

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Biomineralized tetramethylpyrazine-loaded PCL/Gelatin nanofibrous membrane promotes vascularization and bone regeneration of rat cranium defectsDOI 10.21203/rs.3.rs-3294726/v1
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