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Article

Inducing functional radial glia-like progenitors from cortical astrocyte cultures using micropatterned PMMA.

Biomaterials - 1 Feb 2012

Mattotti Marta, Alvarez Zaida, Ortega Juan A, Planell Josep A, Engel Elisabeth, Alcántara Soledad

Abstract excerpt

Radial glia cells (RGC) are multipotent progenitors that generate neurons and glia during CNS development, and which also served as substrate for neuronal migration. After a lesion, reactive glia are the main contributor to CNS regenerative blockage, although some reactive astrocytes are also able to de-differentiate in situ into radial glia-like cells (RGLC), providing beneficial effects in terms of CNS...

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Identifiers

PMID: 22136716
DOI: 10.1016/j.biomaterials.2011.10.086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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