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Article

Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles.

Biomaterials - 1 Oct 2012

Bible Ellen, Qutachi Omar, Chau David Y S, Alexander Morgan R, Shakesheff Kevin M, Modo Michel

Abstract excerpt

Replacing the tissue lost after a stroke potentially provides a new neural substrate to promote recovery. However, significant neurobiological and biotechnological challenges need to be overcome to make this possibility into a reality. Human neural stem cells (hNSCs) can differentiate into mature brain cells, but require a structural support that retains them within the cavity and affords the formation of a de...

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Identifiers

PMID: 22818980
DOI: 10.1016/j.biomaterials.2012.06.085
PMCID: PMC3418478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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