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Core Promoter and Pre-Core Variants of the Hepatitis B Virus (HBV) Are Frequent in Chronic Hepatitis B HBeAg-Negative Patients Infected by Genotypes A and D.

Viruses - 29 Nov 2023

Reuter Tania, Gomes-Gouvea Michele Soares, Chuffi Samira, Duque Ulisses Horst, Perini Waltesia, Azevedo Raymundo Soares, Pinho João Renato Rebello

Abstract excerpt

In Brazil, hepatitis B virus endemicity is low, moderate, or high in some areas, such as Espírito Santo State in the southeast region. In this study, we intend to characterize the basal core promoter (BCP) and pre-core region (PC) variants and their association with clinical/epidemiological disease patterns in patients infected with genotypes A and D. The study included 116 chronic hepatitis B patients from...

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Identifiers

PMID: 38140580
DOI: 10.3390/v15122339
PMCID: PMC10746983

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