Article
Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma.
Journal of the National Cancer Institute - 6 Aug 2008
Xing Jinliang, Chen Meng, Wood Christopher G, Lin Jie, Spitz Margaret R, Ma Jianzhong, Amos Christopher I, Shields Peter G, Benowitz Neal L, Gu Jian, de Andrade Mariza, Swan Gary E, Wu Xifeng
Abstract excerpt
BACKGROUND: The extent to which mitochondrial DNA (mtDNA) content (also termed mtDNA copy number) in normal human cells is influenced by genetic factors has yet to be established. In addition, whether inherited variation of mtDNA content in normal cells contributes to cancer susceptibility remain...
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