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Article

Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma.

Journal of the National Cancer Institute - 6 Aug 2008

Xing Jinliang, Chen Meng, Wood Christopher G, Lin Jie, Spitz Margaret R, Ma Jianzhong, Amos Christopher I, Shields Peter G, Benowitz Neal L, Gu Jian, de Andrade Mariza, Swan Gary E, Wu Xifeng

Abstract excerpt

BACKGROUND: The extent to which mitochondrial DNA (mtDNA) content (also termed mtDNA copy number) in normal human cells is influenced by genetic factors has yet to be established. In addition, whether inherited variation of mtDNA content in normal cells contributes to cancer susceptibility remains unclear. Renal cell carcinoma accounts for 85% of all renal cancers. No studies have investigated the association...

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Identifiers

PMID: 18664653
DOI: 10.1093/jnci/djn213
PMCID: PMC2720693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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