Article
The Helicobacter pylori blood group antigen-binding adhesin facilitates bacterial colonization and augments a nonspecific immune response.
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2002
Rad Roland, Gerhard Markus, Lang Roland, Schöniger Martin, Rösch Thomas, Schepp Wolfgang, Becker Ingrid, Wagner Hermann, Prinz Christian
Abstract excerpt
Presence of the Helicobacter pylori adherence factor blood group Ag-binding adhesin (BabA; binding to Lewis(b) (Le(b))) is associated with ulcer disease, adenocarcinoma, and precancerous lesions. The importance of BabA for bacterial colonization and the inflammatory response is unknown. A total of 141 antral biopsies from H. pylori-infected patients were assessed in regard to the degree of granulocytic (G0...
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