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Helicobacter pylori Lewis expression is related to the host Lewis phenotype.

Gastroenterology - 1 Oct 1997

Wirth H P, Yang M, Peek R M, Tham K T, Blaser M J

Abstract excerpt

BACKGROUND & AIMS: Lewis antigens occur in human gastric epithelium and in Helicobacter pylori lipopolysaccharide; their expression is polymorphic in both. Autoimmune mechanisms induced by bacterial Lewis expression have been proposed to cause gastritis. The aim of this study was to examine the relationship between bacterial and host gastric Lewis expression, as determined by the erythrocyte Lewis(a/b) phenotype,...

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Identifiers

PMID: 9322503
DOI: 10.1053/gast.1997.v113.pm9322503

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